iPTMnet Report for P35858 (IGFALS)
Protein Information
| UniProt AC / UniProt ID | P35858 / ALS_HUMAN |
| Protein Name | Insulin-like growth factor-binding protein complex acid labile subunit precursor |
| Gene Name | Name: IGFALS Synonyms:ALS; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35858 |
| PRO Name | insulin-like growth factor-binding protein complex acid labile subunit (human) |
| Definition | An insulin-like growth factor-binding protein complex acid labile chain that is encoded in the genome of human. |
| Short Label | hIGFALS |
| Category | organism-gene |
DAG ViewP35858 (IGFALS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T32 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N368 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 29741879, 19159218, ... | ||
| T407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y510 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N515 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
| S517 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N580 | N-Glycosylation | score1 | GlyGen | 29741879 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T32 | K32 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S512 | N512 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
