iPTMnet Report for P35716 (SOX11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35716 / SOX11_HUMAN
Protein Name Transcription factor SOX-11
Gene Name Name: SOX11
Organism Homo sapiens (Human)

PRO ID PR:P35716
DAG View
PRO Name transcription factor SOX-11 (human)
Definition A transcription factor SOX-11 that is encoded in the genome of human.
Short Label hSOX11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35716 (SOX11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K91 Sumoylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S133 Phosphorylation RLIMS-P 30385877
S137 Phosphorylation PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
T159 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S206 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S278 Phosphorylation HPRD   PhosphoSitePlus 15345747
S287 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
C417 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S60 Y60 Biomuta DOID:4159 / skin cancer [ cosmic ]
S60 F60 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K117 E117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S133 T133 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S133 C133 Biomuta DOID:1324 / lung cancer [ cosmic ]
K158 E158 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S278 N278 Biomuta DOID:3571 / liver cancer [ cosmic ]
S287 F287 Biomuta DOID:1324 / lung cancer [ cosmic ]