Protein Information

Cytoscape View


UniProt AC / UniProt ID P35680 / HNF1B_HUMAN
Protein Name Hepatocyte nuclear factor 1-beta
Gene Name Name: HNF1B
Synonyms:TCF2;
Organism Homo sapiens (Human)

PRO ID PR:P35680
DAG View
PRO Name hepatocyte nuclear factor 1-beta (human)
Definition A hepatocyte nuclear factor 1-beta that is encoded in the genome of human.
Short Label hHNF1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35680 (HNF1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S75 T75 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S279 P279 Biomuta DOID:1319 / brain cancer [ icgc ]