iPTMnet Report for P35638 (DDIT3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35638 / DDIT3_HUMAN
Protein Name DNA damage-inducible transcript 3 protein
Gene Name Name: DDIT3
Synonyms:CHOP,CHOP10,GADD153;
Organism Homo sapiens (Human)

PRO ID PR:P35638
DAG View
PRO Name DNA damage-inducible transcript 3 protein (human)
Definition A DNA damage-inducible transcript 3 protein that is encoded in the genome of human.
Short Label hDDIT3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35638 (DDIT3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   Signor 12876286
S15 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   Signor 12876286
S30 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 12876286, 27650555
S31 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   Signor 12876286
S49 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
S79 Phosphorylation Q16539 (MAPK14) phospho.ELM   PhosphoSitePlus   Signor 8650547
S82 Phosphorylation Q16539 (MAPK14) phospho.ELM   PhosphoSitePlus 8650547
Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation P68400 (CSNK2A1) HPRD 12876286
S15 Phosphorylation P68400 (CSNK2A1) HPRD 12876286
S30 Phosphorylation P68400 (CSNK2A1) HPRD 12876286
S31 Phosphorylation P68400 (CSNK2A1) HPRD 12876286
S79 Phosphorylation Q16539 (MAPK14) HPRD 8650547
S82 Phosphorylation Q16539 (MAPK14) HPRD 8650547


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 L31 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]
T64 P64 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]