Protein Information

Cytoscape View

UniProt AC / UniProt ID P35625 / TIMP3_HUMAN
Protein Name Metalloproteinase inhibitor 3 precursor
Gene Name Name: TIMP3
Organism Homo sapiens (Human)

PRO ID PR:P35625
DAG View
PRO Name metalloproteinase inhibitor 3 (human)
Definition A metalloproteinase inhibitor 3 that is encoded in the genome of human.
Short Label hTIMP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P35625 (TIMP3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K45 Acetylation PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K65 Acetylation PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K50 N50 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K65 R65 Biomuta DOID:10534 / stomach cancer [ tcga ]
Y100 C100 Biomuta DOID:363 / uterine cancer [ tcga ]