iPTMnet Report for P35625 (TIMP3)
Protein Information
| UniProt AC / UniProt ID | P35625 / TIMP3_HUMAN |
| Protein Name | Metalloproteinase inhibitor 3 precursor |
| Gene Name | Name: TIMP3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35625 |
| PRO Name | metalloproteinase inhibitor 3 (human) |
| Definition | A metalloproteinase inhibitor 3 that is encoded in the genome of human. |
| Short Label | hTIMP3 |
| Category | organism-gene |
DAG ViewP35625 (TIMP3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K45 | Acetylation | score1 | PhosphoSitePlus | |||
| K49 | Acetylation | score1 | PhosphoSitePlus | |||
| K50 | Acetylation | score1 | PhosphoSitePlus | |||
| K65 | Acetylation | score1 | PhosphoSitePlus | |||
| K68 | Acetylation | score1 | PhosphoSitePlus | |||
| C91 | Methylation | score1 | IEDB | 31844290 | ||
| K99 | Acetylation | score1 | PhosphoSitePlus | |||
| Y100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K112 | Acetylation | score1 | PhosphoSitePlus | |||
| Y177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y195 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K49 | N49 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K50 | N50 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K65 | E65 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K65 | R65 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y100 | C100 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y182 | N182 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
