Protein Information

Cytoscape View


UniProt AC / UniProt ID P35580 / MYH10_HUMAN
Protein Name Myosin-10
Gene Name Name: MYH10
Organism Homo sapiens (Human)

PRO ID PR:P35580
DAG View
PRO Name myosin-10 (human)
Definition A myosin-10 that is encoded in the genome of human.
Short Label hMYH10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35580 (MYH10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y13 Phosphorylation PhosphoSitePlus
R18 Methylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
T31 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
R163 Methylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus
K235 Acetylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
Y285 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
K362 Acetylation PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
K410 Acetylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
K442 Acetylation PhosphoSitePlus   UniProt 19608861
K552 Acetylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
K572 Acetylation PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
K594 Methylation PhosphoSitePlus
R613 Methylation PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K658 Methylation PhosphoSitePlus
T667 Phosphorylation PhosphoSitePlus
K689 Acetylation PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
R718 Methylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
K744 Ubiquitination PhosphoSitePlus
Y761 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
K767 Acetylation PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
C823 S-Nitrosylation dbSNO 2212679, 22126794
Y826 Phosphorylation PhosphoSitePlus
K828 Acetylation PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K842 Ubiquitination PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
K968 Acetylation PhosphoSitePlus
K968 Ubiquitination PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
R1007 Methylation PhosphoSitePlus
S1013 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K1021 Acetylation PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
S1037 Phosphorylation PhosphoSitePlus
K1059 Ubiquitination PhosphoSitePlus
S1129 Phosphorylation PhosphoSitePlus
S1145 O-Glycosylation GlyGen 23301498, 20305658, 26853435, ...29351928
S1145 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1170 Phosphorylation PhosphoSitePlus
T1187 Phosphorylation PhosphoSitePlus
R1198 Methylation PhosphoSitePlus
T1203 Phosphorylation PhosphoSitePlus
K1224 Acetylation PhosphoSitePlus
T1231 Phosphorylation PhosphoSitePlus
K1247 Acetylation PhosphoSitePlus
K1256 Acetylation PhosphoSitePlus
K1267 Ubiquitination PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
S1335 Phosphorylation PhosphoSitePlus
K1345 Acetylation PhosphoSitePlus
T1376 Phosphorylation PhosphoSitePlus
K1379 Acetylation PhosphoSitePlus
K1396 Acetylation PhosphoSitePlus
K1399 Ubiquitination PhosphoSitePlus
Y1415 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S1444 Phosphorylation PhosphoSitePlus
K1448 Acetylation PhosphoSitePlus
K1451 Acetylation PhosphoSitePlus
K1452 Acetylation PhosphoSitePlus
K1452 Methylation PhosphoSitePlus
K1452 Ubiquitination PhosphoSitePlus
K1461 Acetylation PhosphoSitePlus
Y1467 Phosphorylation PhosphoSitePlus
K1484 Acetylation PhosphoSitePlus
K1484 Ubiquitination PhosphoSitePlus
S1487 Phosphorylation PhosphoSitePlus
S1518 Phosphorylation PhosphoSitePlus
S1519 Phosphorylation PhosphoSitePlus
R1545 Methylation PhosphoSitePlus
T1558 Phosphorylation PhosphoSitePlus
K1562 Ubiquitination PhosphoSitePlus
T1582 Phosphorylation PhosphoSitePlus
R1609 Methylation PhosphoSitePlus
K1645 Acetylation PhosphoSitePlus   UniProt 19608861
K1649 Acetylation PhosphoSitePlus
K1649 Ubiquitination PhosphoSitePlus
S1698 Phosphorylation PhosphoSitePlus
S1699 Phosphorylation PhosphoSitePlus
T1768 Phosphorylation PhosphoSitePlus
K1800 Acetylation PhosphoSitePlus
K1800 Ubiquitination PhosphoSitePlus
S1810 Phosphorylation IntAct 18675813
T1815 Phosphorylation IntAct 18675813
K1874 Acetylation PhosphoSitePlus
S1899 Phosphorylation PhosphoSitePlus
S1922 Phosphorylation PhosphoSitePlus
T1923 Phosphorylation PhosphoSitePlus
R1930 Methylation PhosphoSitePlus
S1935 Phosphorylation IntAct   PhosphoSitePlus   UniProt 23186163, 18675813, 24275569
S1937 Phosphorylation Q05513 (PRKCZ) IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 18669648, 16611744, 23186163, ...18675813
S1938 Phosphorylation IntAct   PhosphoSitePlus   UniProt 21406692, 18675813
S1939 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18675813, 24275569, ...19690332
R1940 Methylation PhosphoSitePlus
S1941 Phosphorylation IntAct 18675813
S1952 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 9485326, ...24275569
S1956 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18318008, 18669648, ...9485326, 24275569, 19690332, 20068231
T1960 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569, 9485326
S1962 Phosphorylation PhosphoSitePlus
T1964 Phosphorylation PhosphoSitePlus
S1965 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 9485326
T1970 Phosphorylation PhosphoSitePlus
S1975 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 9485326
Site PTM Type PTM Enzyme Score Source PMID
S214 Phosphorylation PhosphoSitePlus
K1104 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S213 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P35580 (MYH10) S1941 Q96QT4 (TRPM7) unknown eFIP 18675813
Phosphorylation P35580 (MYH10) S1941 Q9BX84 (TRPM6) unknown eFIP 18675813


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 N78 Biomuta DOID:1612 / breast cancer [ cosmic ]
K83 T83 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S85 F85 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T94 A94 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K206 N206 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S227 L227 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y826 C826 Biomuta DOID:1909 / melanoma [ cosmic ]
R1007 C1007 Biomuta DOID:9256 / colorectal cancer [ tcga ]
R1007 H1007 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T1170 I1170 Biomuta DOID:1909 / melanoma [ cosmic ]
T1170 K1170 Biomuta DOID:3571 / liver cancer [ icgc ]
R1198 I1198 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K1345 N1345 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K1396 R1396 Biomuta DOID:10534 / stomach cancer [ icgc, tcga ]
K1452 E1452 Biomuta DOID:363 / uterine cancer [ tcga ]
T1768 I1768 Biomuta DOID:10534 / stomach cancer [ tcga ]
S1810 F1810 Biomuta DOID:363 / uterine cancer [ tcga ]
K1874 N1874 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
R1930 W1930 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R1940 Q1940 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S1941 Y1941 Biomuta DOID:363 / uterine cancer [ tcga ]
S1941 P1941 Biomuta DOID:9256 / colorectal cancer [ tcga ]