iPTMnet Report for P35573 (AGL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35573 / GDE_HUMAN
Protein Name Glycogen debranching enzyme
Gene Name Name: AGL
Synonyms:GDE;
Organism Homo sapiens (Human)

PRO ID PR:P35573
DAG View
PRO Name glycogen debranching enzyme (human)
Definition A glycogen debranching enzyme that is encoded in the genome of human.
Short Label hAGL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35573 (AGL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus   UniProt 24275569
C81 Methylation IEDB 31844290
Y106 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
R322 Methylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
C453 Methylation IEDB 31844290
Y479 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
K510 Acetylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
Y584 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S586 Phosphorylation PhosphoSitePlus
Y638 Phosphorylation PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K816 Acetylation PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
K826 Acetylation PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
K889 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus
S1060 Phosphorylation PhosphoSitePlus
T1130 O-Glycosylation GlyGen 30379171, 34019948, 28510447, ...34725712, 30397120
T1130 Phosphorylation PhosphoSitePlus
T1245 Phosphorylation PhosphoSitePlus
K1262 Ubiquitination PhosphoSitePlus
T1277 Phosphorylation PhosphoSitePlus
S1290 Phosphorylation PhosphoSitePlus
K1291 Ubiquitination PhosphoSitePlus
K1330 Ubiquitination PhosphoSitePlus
K1337 Ubiquitination PhosphoSitePlus
K1351 Ubiquitination PhosphoSitePlus
K1358 Ubiquitination PhosphoSitePlus
K1399 Ubiquitination PhosphoSitePlus
K1406 Acetylation PhosphoSitePlus
Y1464 Phosphorylation PhosphoSitePlus
S1466 Phosphorylation PhosphoSitePlus
T1474 O-Glycosylation GlyGen 30379171, 34019948, 28510447, ...34725712, 30397120
T1477 Phosphorylation IEDB 32387766
Site PTM Type PTM Enzyme Score Source PMID
Y584 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
Y568 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y29 H29 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T56 A56 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y106 H106 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y106 N106 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S171 P171 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S283 F283 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R322 K322 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K415 Q415 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S586 G586 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K875 T875 Biomuta DOID:3571 / liver cancer [ cosmic ]
S894 F894 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S894 A894 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1277 I1277 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1466 F1466 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]