iPTMnet Report for P35557 (GCK)
Protein Information
| UniProt AC / UniProt ID | P35557 / HXK4_HUMAN |
| Protein Name | Hexokinase-4 |
| Gene Name | Name: GCK |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35557 |
| PRO Name | hexokinase-4 (human) |
| Definition | A hexokinase-4 that is encoded in the genome of human. |
| Short Label | hGCK |
| Category | organism-gene |
DAG ViewP35557 (GCK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K161 | Sumoylation | score1 | PhosphoSitePlus | |||
| K169 | Sumoylation | score1 | PhosphoSitePlus | |||
| K346 | Sumoylation | score1 | PhosphoSitePlus | |||
| C371 | S-Nitrosylation | score2 | dbSNO | 22178444, 12707306, 15688001 | ||
| S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S411 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K414 | Sumoylation | score1 | PhosphoSitePlus | |||
| K458 | Sumoylation | score1 | PhosphoSitePlus | |||
| K459 | Sumoylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K169 | N169 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K459 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
