iPTMnet Report for P35499 (SCN4A)
Protein Information
| UniProt AC / UniProt ID | P35499 / SCN4A_HUMAN |
| Protein Name | Sodium channel protein type 4 subunit alpha |
| Gene Name | Name: SCN4A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35499 |
| PRO Name | sodium channel protein type 4 subunit alpha (human) |
| Definition | A sodium channel protein type 4 subunit alpha that is encoded in the genome of human. |
| Short Label | hSCN4A |
| Category | organism-gene |
DAG ViewP35499 (SCN4A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T187 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N362 | N-Glycosylation | score3 | GlyGen UniProt | 30190309 | ||
| T457 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1205 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 30190309 | ||
| K1318 | Acetylation | score1 | PhosphoSitePlus | |||
| S1711 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1715 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1719 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1720 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1721 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1746 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1786 | N-Glycosylation | score1 | GlyGen | 29671580 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T231 | M231 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S1711 | Y1711 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
