iPTMnet Report for P35442 (THBS2)
Protein Information
| UniProt AC / UniProt ID | P35442 / TSP2_HUMAN |
| Protein Name | Thrombospondin-2 precursor |
| Gene Name | Name: THBS2 Synonyms:TSP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35442 |
| PRO Name | thrombospondin-2 (human) |
| Definition | A thrombospondin-2 that is encoded in the genome of human. |
| Short Label | hTHBS2 |
| Category | organism-gene |
DAG ViewP35442 (THBS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N151 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T251 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T252 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S259 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| N316 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N330 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S479 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N584 | N-Glycosylation | score3 | GlyGen UniProt | 16186819 | ||
| N710 | N-Glycosylation | score3 | GlyGen UniProt | 16186819 | ||
| Y1024 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1031 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1035 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1038 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1069 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 29741879, 16186819, ... |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S109 | V109 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T251 | S251 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T252 | N252 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S259 | L259 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S259 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| N316 | H316 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S318 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S399 | Y399 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
