Protein Information

Cytoscape View


UniProt AC / UniProt ID P35241 / RADI_HUMAN
Protein Name Radixin
Gene Name Name: RDX
Organism Homo sapiens (Human)

PRO ID PR:P35241
DAG View
PRO Name radixin (human)
Definition A radixin that is encoded in the genome of human.
Short Label hRDX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35241 (RDX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
T66 Phosphorylation PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
R151 Methylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
K253 Acetylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K258 Acetylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K262 Acetylation PhosphoSitePlus
K262 Sumoylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K263 Acetylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus
R273 Methylation PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
K306 Methylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K344 Acetylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
T542 Phosphorylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
K556 Acetylation PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
Y562 Phosphorylation PhosphoSitePlus
T564 Phosphorylation Q04759 (PRKCQ) , P41279 (MAP3K8) , P25098 (GRK2) , O94804 (STK10) , O95819 (MAP4K4) , O75116 (ROCK2) , Q5S007 (LRRK2) , Q13464 (ROCK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P 15676024, 26500117, 19913059, ...19255442, 17447891, 25799996, 19804365, 9456324, 27178239
T573 Phosphorylation phospho.ELM 9456324
K574 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T66 Phosphorylation HPRD 20068231
T369 Phosphorylation HPRD 20068231
T542 Phosphorylation HPRD 18452278
T545 Phosphorylation HPRD 20068231
T564 Phosphorylation Q13464 (ROCK1) HPRD 9456324, 20068231
T573 Phosphorylation Q13464 (ROCK1) HPRD 9456324


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K72 I72 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K79 T79 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K79 N79 Biomuta DOID:1324 / lung cancer [ cosmic ]
K237 N237 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K253 N253 Biomuta DOID:3571 / liver cancer [ tcga ]
K254 T254 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K258 T258 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
Y270 C270 Biomuta DOID:9256 / colorectal cancer [ tcga ]
R273 H273 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ] DOID:3070 / malignant glioma [ tcga ]
Y291 C291 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
Y291 F291 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T564 S564 Biomuta DOID:1909 / melanoma [ cosmic ]