iPTMnet Report for P35235 (Ptpn11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35235 / PTN11_MOUSE
Protein Name Tyrosine-protein phosphatase non-receptor type 11
Gene Name Name: Ptpn11
Organism Mus musculus (Mouse)

PRO ID PR:P35235
DAG View
PRO Name tyrosine-protein phosphatase non-receptor type 11 (mouse)
Definition A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of mouse.
Short Label mPTPN11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35235 (Ptpn11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 21183079, 18034455, ...17947660
Y63 Phosphorylation PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus   UniProt 18034455
K91 Ubiquitination PhosphoSitePlus
C104 S-Nitrosylation dbSNO 26338901, 21278135
K198 Acetylation PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation P52332 (Jak1) , Q62120 (Jak2) IntAct   phospho.ELM   PhosphoSitePlus 8995399, 7522233
Y327 Phosphorylation Q62120 (Jak2) , P52332 (Jak1) phospho.ELM   PhosphoSitePlus 8995399
Y511 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
K538 Phosphorylation IntAct 11684012
Y542 Phosphorylation IntAct   PhosphoSitePlus   RLIMS-P   UniProt 33033382, 11684012, 11432792, ...27417137, 12531430, 12403768, 28352079, 16885344, 7522233
T543 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
Y580 Phosphorylation IntAct   PhosphoSitePlus   UniProt 16885344, 11432792, 12531430, ...8622870, 8959326
S591 Phosphorylation PhosphoSitePlus


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000044464 (mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1) Interaction PR:P35235 (mPTPN11) PRO 9867848