Protein Information

Cytoscape View


UniProt AC / UniProt ID P35226 / BMI1_HUMAN
Protein Name Polycomb complex protein BMI-1
Gene Name Name: BMI1
Synonyms:PCGF4,RNF51;
Organism Homo sapiens (Human)

PRO ID PR:P35226
DAG View
PRO Name Polycomb complex protein BMI-1 (human)
Definition A Polycomb complex protein BMI-1 that is encoded in the genome of human.
Short Label hBMI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35226 (BMI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
K73 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K88 Sumoylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   RLIMS-P 28270146
R114 Methylation PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
Y204 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
S251 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 17081983, 18452278, 19651622, ...28270146, 20068231
S253 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 17081983, 19691289, 19651622, ...28270146, 20068231
S255 O-Glycosylation GlyGen 29485866, 28714959, 29680296
S255 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 17081983, 19691289, 18452278, ...19651622, 28270146, 20068231
S260 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S316 Phosphorylation P31749 (AKT1) PhosphoSitePlus   RLIMS-P 28270146, 23092893


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046489 (hBMI1/PhosSer+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S110 C110 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S269 F269 Biomuta DOID:363 / uterine cancer [ tcga ]
S274 T274 Biomuta DOID:1324 / lung cancer [ tcga ]
S274 N274 Biomuta DOID:1909 / melanoma [ cosmic ]
S315 * Biomuta DOID:1793 / pancreatic cancer [ tcga ]