iPTMnet Report for P35052 (GPC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35052 / GPC1_HUMAN
Protein Name Glypican-1 precursor
Gene Name Name: GPC1
Organism Homo sapiens (Human)

PRO ID PR:P35052
DAG View
PRO Name glypican-1 (human)
Definition A glypican-1 that is encoded in the genome of human.
Short Label hGPC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35052 (GPC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
N79 N-Glycosylation GlyGen   UniProt 23090970, 21932778, 22351761, ...24190977
N116 N-Glycosylation GlyGen   UniProt 24190977, 23090970, 22351761, ...2148568, 21932778, 29741879
Y145 Phosphorylation PhosphoSitePlus
N156 N-Glycosylation GlyGen 23090970
S372 Phosphorylation PhosphoSitePlus
T409 O-Glycosylation GlyGen 25813380
T447 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
S509 O-Glycosylation GlyGen 25813380
S510 O-Glycosylation GlyGen 25813380
T512 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T515 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
Site PTM Type PTM Enzyme Score Source PMID
T447 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N116 Y116 Biomuta DOID:4159 / skin cancer [ cosmic ]
S372 L372 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T512 M512 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T512 R512 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]