Protein Information

Cytoscape View


UniProt AC / UniProt ID P33991 / MCM4_HUMAN
Protein Name DNA replication licensing factor MCM4
Gene Name Name: MCM4
Synonyms:CDC21;
Organism Homo sapiens (Human)

PRO ID PR:P33991
DAG View
PRO Name DNA replication licensing factor MCM4 (human)
Definition A DNA replication licensing factor MCM4 that is encoded in the genome of human.
Short Label hMCM4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P33991 (MCM4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 21406692, 22814378, 20068231
S2 Phosphorylation HPRD   PhosphoSitePlus 19651622
S3 Phosphorylation P24941 (CDK2) HPRD   PhosphoSitePlus   RLIMS-P 19651622, 16519687, 20068231
S6 Phosphorylation HPRD   PhosphoSitePlus 20068231
T7 Phosphorylation P24941 (CDK2) , P06493 (CDK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P 16517729, 12714602, 16519687
S9 Phosphorylation PhosphoSitePlus
R10 Methylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus
R15 Methylation PhosphoSitePlus
R17 Methylation PhosphoSitePlus
T19 Phosphorylation P06493 (CDK1) , P24941 (CDK2) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 16964243, 12714602, 18669648, ...16519687, 20068231
T23 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S26 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163, ...16964243
S31 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17081983, ...20068231
S32 Phosphorylation P24941 (CDK2) , P06493 (CDK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 17081983, 11454864, ...12714602, 18669648, 16519687, 20068231
S34 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
T53 Phosphorylation P24941 (CDK2) HPRD   PhosphoSitePlus 18847512, 20068231
S54 Phosphorylation P24941 (CDK2) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 18220336, 18847512, 16517729, ...11454864, 12714602, 16519687
S61 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S88 Phosphorylation P06493 (CDK1) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 16519687
T91 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
T102 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S105 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...17924679
R108 Methylation PhosphoSitePlus
T110 Phosphorylation P24941 (CDK2) , P06493 (CDK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 12714602, 11454864, ...18669648, 16519687, 20068231, 17924679
S120 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 19651622, 20068231
K123 Acetylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S131 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18452278, 18669648, 19690332, 20068231
S142 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S145 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
K163 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y193 Phosphorylation HPRD 20068231
K216 Methylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
K220 Acetylation PhosphoSitePlus   UniProt 19608861
K220 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S326 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935, 19664994
K349 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
R387 Methylation PhosphoSitePlus
Y394 Phosphorylation HPRD   PhosphoSitePlus 20068231
S406 Phosphorylation HPRD   PhosphoSitePlus 20068231
K409 Ubiquitination PhosphoSitePlus
K413 Methylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K439 Acetylation PhosphoSitePlus
K439 Sumoylation PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K450 Acetylation PhosphoSitePlus   UniProt 19608861
K450 Ubiquitination PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
Y459 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
K477 Sumoylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
Y522 Phosphorylation PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K627 Acetylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
Y714 Phosphorylation PhosphoSitePlus
R724 Methylation PhosphoSitePlus
S736 Phosphorylation HPRD   PhosphoSitePlus 20068231
K746 Ubiquitination PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K762 Ubiquitination PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
T788 Phosphorylation PhosphoSitePlus
K798 Ubiquitination PhosphoSitePlus
K806 Methylation PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
K819 Acetylation PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
R828 Methylation PhosphoSitePlus
K837 Ubiquitination PhosphoSitePlus
K858 Acetylation PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus