iPTMnet Report for P33240 (CSTF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P33240 / CSTF2_HUMAN
Protein Name Cleavage stimulation factor subunit 2
Gene Name Name: CSTF2
Organism Homo sapiens (Human)

PRO ID PR:P33240
DAG View
PRO Name cleavage stimulation factor subunit 2 (human)
Definition A cleavage stimulation factor subunit 2 that is encoded in the genome of human.
Short Label hCSTF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P33240 (CSTF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
K96 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S154 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K189 Ubiquitination PhosphoSitePlus
R303 Methylation PhosphoSitePlus
R308 Methylation PhosphoSitePlus   UniProt 24129315
S310 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
R319 Methylation PhosphoSitePlus
R330 Methylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
R344 Methylation PhosphoSitePlus
R365 Methylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
R388 Methylation PhosphoSitePlus
R402 Methylation PhosphoSitePlus
R405 Methylation PhosphoSitePlus
R423 Methylation PhosphoSitePlus
R428 Methylation PhosphoSitePlus
R458 Methylation PhosphoSitePlus
R463 Methylation PhosphoSitePlus
R468 Methylation PhosphoSitePlus   UniProt 24129315
R475 Methylation PhosphoSitePlus   UniProt 24129315
S480 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
R499 Methylation PhosphoSitePlus
T507 Phosphorylation phospho.ELM 17081983
S518 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S524 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17525332, 19690332, ...17081983
T531 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S562 Phosphorylation PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S154 Phosphorylation HPRD 18669648
S480 Phosphorylation HPRD 20068231
S486 Phosphorylation HPRD 20068231
S498 Phosphorylation HPRD 20068231
T507 Phosphorylation HPRD 17081983
S513 Phosphorylation HPRD 17081983
S518 Phosphorylation HPRD 17525332
S524 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
T531 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 P14 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y115 F115 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S310 F310 Biomuta DOID:4159 / skin cancer [ cosmic ]
S310 A310 Biomuta DOID:4159 / skin cancer [ cosmic ]
T317 N317 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R319 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S336 F336 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R344 G344 Biomuta DOID:1324 / lung cancer [ cosmic ]
R381 K381 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R458 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R463 K463 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R468 T468 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K567 N567 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]