iPTMnet Report for P33076 (CIITA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P33076 / C2TA_HUMAN
Protein Name MHC class II transactivator
Gene Name Name: CIITA
Synonyms:MHC2TA;
Organism Homo sapiens (Human)

PRO ID PR:P33076
DAG View
PRO Name MHC class II transactivator (human)
Definition An MHC class II transactivator that is encoded in the genome of human.
Short Label hCIITA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P33076 (CIITA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C46 Methylation IEDB 31844290
K141 Acetylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
S280 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 26181363, 18245089, 20538595, ...15210796, 17095509
S280 Phosphorylation P27361 (MAPK3) neXtProt   PhosphoSitePlus   Signor 17095509, 26181363
S280 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   Signor 17095509, 15210796, 26181363, ...18245089
S286 Phosphorylation PhosphoSitePlus   RLIMS-P 15210796
S288 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18245089, 15210796
S288 Phosphorylation P27361 (MAPK3) PhosphoSitePlus   Signor 18245089
S288 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   Signor 15210796, 18245089
S293 Phosphorylation PhosphoSitePlus   RLIMS-P 15210796
K315 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus   Signor 17991736
S373 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 17991736
S427 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
C769 Methylation IEDB 31844290
S834 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11416140
S834 Phosphorylation P17612 (PRKACA) HPRD   neXtProt   PhosphoSitePlus   Signor 11416140
T838 Phosphorylation PhosphoSitePlus
T916 O-Glycosylation GlyGen 30379171
T947 Phosphorylation PhosphoSitePlus
K959 Acetylation PhosphoSitePlus
S1050 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11416140
S1050 Phosphorylation P17612 (PRKACA) HPRD   neXtProt   PhosphoSitePlus   Signor 11416140
S1073 O-Glycosylation GlyGen 30379171
S1073 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K141 Acetylation PRO 11046145
K141 Acetylation PR:000012332 (KAT2B) PRO 11046145
K141 Acetylation PR:Q92793 (hCREBBP) PRO 11046145
K144 Acetylation PRO 11046145
K144 Acetylation PR:000012332 (KAT2B) PRO 11046145
K144 Acetylation PR:Q92793 (hCREBBP) PRO 11046145


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028745 (hCIITA/iso:1/Ac:1) acK141,acK144 PR:000012332 (KAT2B) PRO 11046145
PR:000028745 (hCIITA/iso:1/Ac:1) acK141,acK144 PR:Q92793 (hCREBBP) PRO 11046145