Protein Information

Cytoscape View


UniProt AC / UniProt ID P32754 / HPPD_HUMAN
Protein Name 4-hydroxyphenylpyruvate dioxygenase
Gene Name Name: HPD
Synonyms:PPD;
Organism Homo sapiens (Human)

PRO ID PR:P32754
DAG View
PRO Name 4-hydroxyphenylpyruvate dioxygenase (human)
Definition A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of human.
Short Label hHPD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P32754 (HPD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 22814378
Y4 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y221 Phosphorylation PhosphoSitePlus
S222 Phosphorylation HPRD   PhosphoSitePlus 20166139
S223 Phosphorylation HPRD   PhosphoSitePlus 20166139
S226 Phosphorylation HPRD 20068231
Y232 Phosphorylation HPRD   PhosphoSitePlus 20068231
K247 Acetylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
T382 Phosphorylation RLIMS-P 31537781


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P32754 (HPD) T382 Q96FA3 (PELI1) decreased_association eFIP 31537781