iPTMnet Report for P32455 (GBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P32455 / GBP1_HUMAN
Protein Name Guanylate-binding protein 1 precursor
Gene Name Name: GBP1
Organism Homo sapiens (Human)

PRO ID PR:P32455
DAG View
PRO Name guanylate-binding protein 1 (human)
Definition A guanylate-binding protein 1 that is encoded in the genome of human.
Short Label hGBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P32455 (GBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
C311 Methylation IEDB 31844290
Y335 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
Y427 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
K544 Methylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K553 Acetylation PhosphoSitePlus
K562 Acetylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S52 Y52 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S52 T52 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S66 F66 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T70 A70 Biomuta DOID:1324 / lung cancer [ cosmic ]
K215 N215 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K232 N232 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K246 T246 Biomuta DOID:1324 / lung cancer [ cosmic ]
K453 N453 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y464 C464 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K544 N544 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K582 N582 Biomuta DOID:4159 / skin cancer [ cosmic ]