iPTMnet Report for P32245 (MC4R)
Protein Information
| UniProt AC / UniProt ID | P32245 / MC4R_HUMAN |
| Protein Name | Melanocortin receptor 4 |
| Gene Name | Name: MC4R |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P32245 |
| PRO Name | melanocortin receptor 4 (human) |
| Definition | A melanocortin receptor 4 that is encoded in the genome of human. |
| Short Label | hMC4R |
| Category | organism-gene |
DAG ViewP32245 (MC4R) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C293 | Methylation | score1 | IEDB | 31844290 | ||
| T312 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) , P17612 (PRKACA) , P25098 (GRK2) | score3 | HPRD phospho.ELM PhosphoSitePlus Signor | 12639913 | |
| S329 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) , P25098 (GRK2) , P17612 (PRKACA) | score3 | HPRD phospho.ELM PhosphoSitePlus Signor | 12639913 | |
| S330 | Phosphorylation | P17612 (PRKACA) , P25098 (GRK2) , A0A0S2Z3I6 (ADRBK1) | score3 | HPRD phospho.ELM PhosphoSitePlus Signor | 12639913 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S330 | G330 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
