Protein Information

Cytoscape View

UniProt AC / UniProt ID P32119 / PRDX2_HUMAN
Protein Name Peroxiredoxin-2
Gene Name Name: PRDX2
Organism Homo sapiens (Human)

PRO ID PR:P32119
DAG View
PRO Name peroxiredoxin-2 (human)
Definition A peroxiredoxin-2 that is encoded in the genome of human.
Short Label hPRDX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P32119 (PRDX2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S3 Phosphorylation PhosphoSitePlus
K10 Acetylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K16 Acetylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
T18 O-Glycosylation GlyGen   PhosphoSitePlus 16408927, 30397120, 26374642, ...32119511, 20305658, 18984734
T18 Phosphorylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K29 Acetylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
R110 Methylation PhosphoSitePlus
S112 O-Glycosylation GlyGen   PhosphoSitePlus 16408927, 30397120, 26374642, ...32119511, 20305658, 18984734
S112 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y115 Phosphorylation PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
R127 Methylation PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
R150 Methylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
R157 Methylation PhosphoSitePlus
K177 Methylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus   UniProt 24275569
S190 Phosphorylation PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
K191 Methylation PhosphoSitePlus
K191 Sumoylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T128 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K26 I26 Biomuta DOID:1324 / lung cancer [ tcga ]
S76 L76 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
T89 I89 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R110 C110 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R110 L110 Biomuta DOID:3070 / malignant glioma [ tcga ]
R110 H110 Biomuta DOID:363 / uterine cancer [ tcga ]
S112 P112 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K119 E119 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R150 C150 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S151 F151 Biomuta DOID:4362 / cervical cancer [ tcga ]
K177 E177 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T182 M182 Biomuta DOID:1909 / melanoma [ cosmic ]
T182 S182 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]