iPTMnet Report for P31997 (CEACAM8)
Protein Information
| UniProt AC / UniProt ID | P31997 / CEAM8_HUMAN |
| Protein Name | Carcinoembryonic antigen-related cell adhesion molecule 8 precursor |
| Gene Name | Name: CEACAM8 Synonyms:CGM6; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P31997 |
| PRO Name | carcinoembryonic antigen-related cell adhesion molecule 8 (human) |
| Definition | A carcinoembryonic antigen-related cell adhesion molecule 8 that is encoded in the genome of human. |
| Short Label | hCEACAM8 |
| Category | organism-gene |
DAG ViewP31997 (CEACAM8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K126 | Methylation | score1 | PhosphoSitePlus | |||
| N173 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| N197 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| N288 | N-Glycosylation | score2 | GlyGen UniProt | 16740002 | ||
| S296 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y120 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K126 | Q126 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| N173 | S173 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| N197 | S197 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S296 | F296 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
