iPTMnet Report P31994 FCGR2B

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P31994 / FCG2B_HUMAN
Protein Name	Low affinity immunoglobulin gamma Fc region receptor II-b precursor
Gene Name	Name: FCGR2B Synonyms:CD32,FCG2,IGFR2;
Organism	Homo sapiens (Human)

PRO ID	PR:P31994 DAG View
PRO Name	low affinity immunoglobulin gamma Fc region receptor II-b (human)
Definition	A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human.
Short Label	hFCGR2B
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P31994 (FCGR2B) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N180	N-Glycosylation		score1	GlyGen	24190977
	N187	N-Glycosylation		score1	GlyGen	24190977
	N199	N-Glycosylation		score1	GlyGen	24190977
	Y292	Phosphorylation	P06241 (FYN) , P07948 (LYN) , P51451 (BLK)	score4	IntAct neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt	8756631, 33409482, 10382761, ...8577729, 9603468, 10704309, 9148918
	S293	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y292	Phosphorylation	P07948 (LYN) , P51451 (BLK)	score1	HPRD	8756631
	S293	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S253	Phosphorylation		score1	PhosphoSitePlus
	Y273	Phosphorylation	P51451 (BLK) , P07948 (LYN)	score3	HPRD PhosphoSitePlus	8756631
	S274	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y291	Phosphorylation	P51451 (BLK) , P07948 (LYN)	score1	HPRD	8756631
	S292	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y272	Phosphorylation	P51451 (BLK) , P07948 (LYN)	score1	HPRD	8756631
	S273	Phosphorylation		score0	HPRD	20166139

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N187	S187	Biomuta		DOID:10534 / stomach cancer [ icgc ]