iPTMnet Report for P31949 (S100A11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P31949 / S10AB_HUMAN
Protein Name Protein S100-A11
Gene Name Name: S100A11
Synonyms:MLN70,S100C;
Organism Homo sapiens (Human)

PRO ID PR:P31949
DAG View
PRO Name protein S100-A11 (human)
Definition A protein S100-A11 that is encoded in the genome of human.
Short Label hS100A11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P31949 (S100A11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO   UniProt 22814378
A2 Acetylation UniProt 22814378
K3 Acetylation PhosphoSitePlus   UniProt 19608861
K3 Ubiquitination PhosphoSitePlus
S5 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S6 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 24275569, 20068231, 17081983
T8 Phosphorylation PhosphoSitePlus
T10 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10851017, 20068231, 18618420, ...14623863
C13 Methylation IEDB 31844290
C13 S-Nitrosylation dbSNO 19483679, 22178444, 18335467, ...25040305, 24105792, 19366988
S16 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
Y30 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 18083107, 19901323
Y32 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 18083107
T33 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
R62 Methylation PhosphoSitePlus
K65 Acetylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K66 Acetylation PhosphoSitePlus
T69 Phosphorylation HPRD   PhosphoSitePlus 17081983
S71 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S78 Phosphorylation HPRD 17081983
S94 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 14623863
K97 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036320 (hS100A11/Ac:1) acM1 PRO
PR:000036883 (hS100A11/Phos:1) pY30 PRO
PR:000036884 (hS100A11/Phos:2) pY30,pY32 PRO
PR:000036885 (hS100A11/Phos:3) pY32 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P04083 (ANXA1) S5 P31949 (S100A11) decreased_association eFIP 21280599


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K3 T3 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T8 K8 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K23 R23 Biomuta [ cosmic ]
Y30 N30 Biomuta DOID:3571 / liver cancer [ cosmic ]
S35 F35 Biomuta DOID:363 / uterine cancer [ icgc ]
K55 E55 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S71 I71 Biomuta DOID:1324 / lung cancer [ cosmic ]
S71 G71 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]