Protein Information

Cytoscape View

UniProt AC / UniProt ID P31785 / IL2RG_HUMAN
Protein Name Cytokine receptor common subunit gamma precursor
Gene Name Name: IL2RG
Organism Homo sapiens (Human)

PRO ID PR:P31785
DAG View
PRO Name cytokine receptor common subunit gamma (human)
Definition A cytokine receptor common subunit gamma that is encoded in the genome of human.
Short Label hIL2RG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P31785 (IL2RG) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N71 N-Glycosylation GlyGen   UniProt 16477002, 16293754
N84 N-Glycosylation GlyGen   UniProt 16477002, 16293754
K101 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
N159 N-Glycosylation GlyGen   UniProt 16293754, 16477002, 24190977
K164 Ubiquitination PhosphoSitePlus
N180 N-Glycosylation GlyGen 24190977
K207 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus   UniProt 19690332
K294 Ubiquitination PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
Y325 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y303 Phosphorylation HPRD 19901323
Y357 Phosphorylation HPRD 19901323
Y363 Phosphorylation HPRD 19901323

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K217 T217 Biomuta DOID:363 / uterine cancer [ tcga ]
K294 N294 Biomuta DOID:363 / uterine cancer [ tcga ]
S308 L308 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]