iPTMnet Report for P31785 (IL2RG)
Protein Information
| UniProt AC / UniProt ID | P31785 / IL2RG_HUMAN |
| Protein Name | Cytokine receptor common subunit gamma precursor |
| Gene Name | Name: IL2RG |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P31785 |
| PRO Name | cytokine receptor common subunit gamma (human) |
| Definition | A cytokine receptor common subunit gamma that is encoded in the genome of human. |
| Short Label | hIL2RG |
| Category | organism-gene |
DAG ViewP31785 (IL2RG) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C62 | Methylation | score1 | IEDB | 31844290 | ||
| N71 | N-Glycosylation | score4 | GlyGen UniProt | 16477002, 16293754 | ||
| N84 | N-Glycosylation | score4 | GlyGen UniProt | 16477002, 16293754 | ||
| K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C115 | Methylation | score1 | IEDB | 31844290 | ||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N159 | N-Glycosylation | score4 | GlyGen UniProt | 16293754, 16477002, 24190977 | ||
| K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S166 | Phosphorylation | score1 | IEDB | 35494241 | ||
| N180 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| C182 | Methylation | score1 | IEDB | 31844290 | ||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T292 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| K294 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y325 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C330 | Methylation | score1 | IEDB | 31844290 | ||
| Y357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y363 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N84 | K84 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] | |
| K217 | T217 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K294 | N294 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] | |
| Y303 | S303 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S308 | L308 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K315 | N315 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
