iPTMnet Report for P31689 (DNAJA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P31689 / DNJA1_HUMAN
Protein Name DnaJ homolog subfamily A member 1 precursor
Gene Name Name: DNAJA1
Synonyms:DNAJ2,HDJ2,HSJ2,HSPF4;
Organism Homo sapiens (Human)

PRO ID PR:P31689
DAG View
PRO Name DnaJ homolog subfamily A member 1 (human)
Definition A DnaJ homolog subfamily A member 1 that is encoded in the genome of human.
Short Label hDNAJA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P31689 (DNAJA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
Y8 Phosphorylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K44 Acetylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K66 Acetylation PhosphoSitePlus   UniProt 19608861
K66 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 19690332, ...20068231, 17924679
K105 Ubiquitination PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
R253 Methylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
C302 Methylation IEDB 31844290
C302 S-Nitrosylation dbSNO 26338901
Y311 Phosphorylation PhosphoSitePlus
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...18669648, 19690332, 20068231, 17924679
K338 Ubiquitination PhosphoSitePlus
S340 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K344 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
Y381 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 18083107
Site PTM Type PTM Enzyme Score Source PMID
S83 Phosphorylation HPRD 19413330, 18691976, 17924679, ...20068231, 18452278
S175 Phosphorylation HPRD 20068231
S188 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 19413330, 18691976, 20058876, ...19664994, 19651622, 17322306, 18669648, 18767875, 20068231, 17924679
S340 Phosphorylation HPRD 18669648, 17081983, 20068231
Y381 Phosphorylation HPRD 15592455, 19901323


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K3 N3 Biomuta DOID:263 / kidney cancer [ cosmic ]
S49 A49 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K130 N130 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K143 E143 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R253 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
R253 L253 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R253 Q253 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K296 E296 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y376 C376 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]