iPTMnet Report for P31483 (TIA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P31483 / TIA1_HUMAN
Protein Name Cytotoxic granule associated RNA binding protein TIA1
Gene Name Name: TIA1
Organism Homo sapiens (Human)

PRO ID PR:P31483
DAG View
PRO Name cytotoxic granule associated RNA binding protein TIA1 (human)
Definition A cytotoxic granule associated RNA binding protein TIA1 that is encoded in the genome of human.
Short Label hTIA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P31483 (TIA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y48 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
R131 Methylation PhosphoSitePlus
K139 Methylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
S209 Phosphorylation phospho.ELM   PhosphoSitePlus 16094384
S210 Phosphorylation phospho.ELM   PhosphoSitePlus 16094384
S235 Phosphorylation PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S209 Phosphorylation HPRD 16094384
S210 Phosphorylation HPRD 16094384
Site PTM Type PTM Enzyme Score Source PMID
K89 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S198 Phosphorylation HPRD 16094384
S199 Phosphorylation HPRD 16094384


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T99 S99 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y383 C383 Biomuta DOID:2531 / hematologic cancer [ cosmic ]