iPTMnet Report for P31321 (PRKAR1B)
Protein Information
UniProt AC / UniProt ID | P31321 / KAP1_HUMAN |
Protein Name | cAMP-dependent protein kinase type I-beta regulatory subunit |
Gene Name | Name: PRKAR1B |
Organism | Homo sapiens (Human) |
PRO ID | PR:P31321 |
PRO Name | cAMP-dependent protein kinase type I-beta regulatory subunit (human) |
Definition | A cAMP-dependent protein kinase type I-beta regulatory subunit that is encoded in the genome of human. |
Short Label | hPRKAR1B |
Category | organism-gene |
P31321 (PRKAR1B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163 | ||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S71 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976, 18669648 | ||
S77 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648 | ||
S83 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163, 18669648, ... | ||
T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T209 | Phosphorylation | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y246 | Phosphorylation | score1 | PhosphoSitePlus | |||
S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y312 | Phosphorylation | score1 | PhosphoSitePlus | |||
T338 | Phosphorylation | score1 | PhosphoSitePlus | |||
R342 | Methylation | score1 | PhosphoSitePlus | |||
K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | F3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S9 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S9 | L9 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S14 | G14 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S71 | L71 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
S73 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
S75 | L75 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S77 | F77 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y207 | N207 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T209 | I209 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T239 | M239 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] | |
T338 | I338 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R342 | W342 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |