iPTMnet Report for P31321 (PRKAR1B)
Protein Information
| UniProt AC / UniProt ID | P31321 / KAP1_HUMAN |
| Protein Name | cAMP-dependent protein kinase type I-beta regulatory subunit |
| Gene Name | Name: PRKAR1B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P31321 |
| PRO Name | cAMP-dependent protein kinase type I-beta regulatory subunit (human) |
| Definition | A cAMP-dependent protein kinase type I-beta regulatory subunit that is encoded in the genome of human. |
| Short Label | hPRKAR1B |
| Category | organism-gene |
P31321 (PRKAR1B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163 | ||
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S71 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
| S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976, 18669648 | ||
| S77 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648 | ||
| S83 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163, 18669648, ... | ||
| T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T209 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y312 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R342 | Methylation | score1 | PhosphoSitePlus | |||
| K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K349 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S3 | F3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S9 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S9 | L9 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S14 | G14 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S71 | L71 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| S73 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S75 | L75 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S77 | F77 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y207 | N207 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T209 | I209 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T239 | M239 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] | |
| T338 | I338 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R342 | W342 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View