iPTMnet Report for P30874 (SSTR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30874 / SSR2_HUMAN
Protein Name Somatostatin receptor type 2
Gene Name Name: SSTR2
Organism Homo sapiens (Human)

PRO ID PR:P30874
DAG View
PRO Name somatostatin receptor type 2 (human)
Definition A somatostatin receptor type 2 that is encoded in the genome of human.
Short Label hSSTR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30874 (SSTR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y66 Phosphorylation PhosphoSitePlus
R70 Phosphorylation IntAct 16917505
Y71 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K248 Acetylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus   RLIMS-P 21330405, 24565897
S341 Phosphorylation P35626 (GRK3) PhosphoSitePlus 21330405
S343 Phosphorylation PhosphoSitePlus   RLIMS-P 21330405, 24565897
S343 Phosphorylation P35626 (GRK3) PhosphoSitePlus 21330405
T353 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R70 C70 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ]
Y71 H71 Biomuta DOID:4159 / skin cancer [ cosmic ]
S343 N343 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T353 N353 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T353 S353 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T354 M354 Biomuta DOID:184 / bone cancer [ cosmic ]
T356 A356 Biomuta DOID:3571 / liver cancer [ cosmic ]