iPTMnet Report for P30825 (SLC7A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30825 / CTR1_HUMAN
Protein Name High affinity cationic amino acid transporter 1
Gene Name Name: SLC7A1
Synonyms:ATRC1;
Organism Homo sapiens (Human)

PRO ID PR:P30825
DAG View
PRO Name high affinity cationic amino acid transporter 1 (human)
Definition A high affinity cationic amino acid transporter 1 that is encoded in the genome of human.
Short Label hSLC7A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30825 (SLC7A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
N226 N-Glycosylation GlyGen   UniProt 29741879, 19349973, 24190977
N235 N-Glycosylation GlyGen 24190977
K373 Ubiquitination PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
C628 S-Nitrosylation dbSNO 26338901
K629 Sumoylation PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K4 E4 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
N226 S226 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K484 N484 Biomuta DOID:1324 / lung cancer [ cosmic ]