iPTMnet Report for P30793 (GCH1)
Protein Information
| UniProt AC / UniProt ID | P30793 / GCH1_HUMAN |
| Protein Name | GTP cyclohydrolase 1 |
| Gene Name | Name: GCH1 Synonyms:DYT5,GCH; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P30793 |
| PRO Name | GTP cyclohydrolase 1 (human) |
| Definition | A GTP cyclohydrolase 1 that is encoded in the genome of human. |
| Short Label | hGCH1 |
| Category | organism-gene |
DAG ViewP30793 (GCH1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S60 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| S81 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 17704208 | ||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y175 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S224 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S223 | Y223 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
