iPTMnet Report P30518 AVPR2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P30518 / V2R_HUMAN
Protein Name	Vasopressin V2 receptor
Gene Name	Name: AVPR2 Synonyms:ADHR,DIR,DIR3,V2R;
Organism	Homo sapiens (Human)

PRO ID	PR:P30518 DAG View
PRO Name	vasopressin V2 receptor (human)
Definition	A vasopressin V2 receptor that is encoded in the genome of human.
Short Label	hAVPR2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P30518 (AVPR2) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
		Phosphorylation		score1	PRO
	Y124	Phosphorylation		score1	PhosphoSitePlus
	S255	Phosphorylation	P17612 (PRKACA) , P22694 (PRKACB)	score3	neXtProt PhosphoSitePlus	18578504
	T347	Phosphorylation		score0	RLIMS-P	32917711
	S350	Phosphorylation		score0	RLIMS-P	32917711
	S357	Phosphorylation		score0	RLIMS-P	32917711
	T359	Phosphorylation		score0	RLIMS-P	32917711
	S362	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P	32917711, 9482866
	S363	Phosphorylation		score3	phospho.ELM PhosphoSitePlus	9482866
	S364	Phosphorylation		score3	phospho.ELM PhosphoSitePlus	9482866
	T369	Phosphorylation		score0	RLIMS-P	32917711

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y325	Phosphorylation		score1	HPRD	12436935

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000046441 (hAVPR2/PhosRes+)	p		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S350	T350	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S357	Y357	Biomuta		DOID:1793 / pancreatic cancer [ icgc ]