iPTMnet Report for P30511 (HLA-F)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30511 / HLAF_HUMAN
Protein Name HLA class I histocompatibility antigen, alpha chain F precursor
Gene Name Name: HLA-F
Synonyms:HLA-5.4;
Organism Homo sapiens (Human)

PRO ID PR:P30511
DAG View
PRO Name HLA class I histocompatibility antigen, alpha chain F (human)
Definition An MHC class I histocompatibility antigen, alpha chain F that is encoded in the genome of human.
Short Label hHLA-F
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30511 (HLA-F) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 O-Glycosylation GlyGen 29351928, 30620550
K89 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
N107 N-Glycosylation GlyGen 24190977
Y139 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
C185 Methylation IEDB 31844290
Y192 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T31 I31 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
N107 S107 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T199 M199 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S216 Y216 Biomuta DOID:9256 / colorectal cancer [ cosmic ]