iPTMnet Report for P30414 (NKTR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30414 / NKTR_HUMAN
Protein Name NK-tumor recognition protein
Gene Name Name: NKTR
Organism Homo sapiens (Human)

PRO ID PR:P30414
DAG View
PRO Name NK-tumor recognition protein (human)
Definition An NK-tumor recognition protein that is encoded in the genome of human.
Short Label hNKTR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30414 (NKTR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K60 Acetylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K179 Sumoylation PhosphoSitePlus
K182 Sumoylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S274 O-Glycosylation GlyGen 30379171
K279 Sumoylation PhosphoSitePlus
K311 Sumoylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K323 Acetylation PhosphoSitePlus
K323 Sumoylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K328 Acetylation PhosphoSitePlus
T343 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983, 20068231
S347 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983, 20068231
T361 Phosphorylation PhosphoSitePlus
Y375 Phosphorylation HPRD 17081983
S379 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17081983, ...20068231
K382 Sumoylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
K388 Sumoylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus   UniProt 23186163
S403 Phosphorylation PhosphoSitePlus
S406 Phosphorylation HPRD 17081983
S408 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
S410 Phosphorylation HPRD   phospho.ELM 17081983
Y414 Phosphorylation HPRD 17081983
Y415 Phosphorylation HPRD 17081983
S416 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 17081983
S463 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...20058876, 19651622, 18669648, 20068231
S467 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S468 Phosphorylation HPRD   PhosphoSitePlus 20068231
K469 Sumoylation PhosphoSitePlus
S470 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231
S471 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 17081983, ...20068231
T472 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S478 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
S509 Phosphorylation HPRD 20068231
S510 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
T570 Phosphorylation PhosphoSitePlus
S572 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S575 Phosphorylation PhosphoSitePlus
K578 Sumoylation PhosphoSitePlus
K581 Sumoylation PhosphoSitePlus
S611 Phosphorylation HPRD   phospho.ELM 18669648, 20068231
S613 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S617 Phosphorylation PhosphoSitePlus
K627 Sumoylation PhosphoSitePlus
K637 Methylation PhosphoSitePlus
K637 Sumoylation PhosphoSitePlus
K639 Methylation PhosphoSitePlus
K639 Sumoylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus   UniProt 23186163
T658 Phosphorylation PhosphoSitePlus
K666 Sumoylation PhosphoSitePlus
Y678 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
S685 O-Glycosylation GlyGen 30379171
S697 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
S724 Phosphorylation HPRD 17081983
S736 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
S801 Phosphorylation IEDB 32357974
S808 Phosphorylation PhosphoSitePlus
K862 Methylation PhosphoSitePlus
K862 Sumoylation PhosphoSitePlus
S866 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S887 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S889 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S891 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18452278
T915 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus
K949 Sumoylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
T990 O-Glycosylation GlyGen 30379171
K1040 Sumoylation PhosphoSitePlus
K1043 Sumoylation PhosphoSitePlus
K1057 Sumoylation PhosphoSitePlus
T1074 Phosphorylation HPRD 20068231
S1076 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1077 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163
S1092 Phosphorylation PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
T1145 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...19664994, 19651622, 20068231
T1155 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 19664994, ...19664995, 24275569, 20068231
K1177 Sumoylation PhosphoSitePlus
K1193 Sumoylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1207 Phosphorylation PhosphoSitePlus
K1210 Sumoylation PhosphoSitePlus
K1216 Sumoylation PhosphoSitePlus
S1217 Phosphorylation PhosphoSitePlus
K1225 Sumoylation PhosphoSitePlus
K1258 Sumoylation PhosphoSitePlus
K1271 Sumoylation PhosphoSitePlus
S1276 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
S1335 Phosphorylation PhosphoSitePlus
S1337 Phosphorylation PhosphoSitePlus
S1339 Phosphorylation PhosphoSitePlus
S1341 Phosphorylation PhosphoSitePlus
S1350 Phosphorylation PhosphoSitePlus
S1352 Phosphorylation PhosphoSitePlus
Y1353 Phosphorylation PhosphoSitePlus
S1354 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation PhosphoSitePlus
S1358 Phosphorylation PhosphoSitePlus
S1363 Phosphorylation PhosphoSitePlus
S1373 Phosphorylation PhosphoSitePlus
Y1377 Phosphorylation PhosphoSitePlus
S1390 O-Glycosylation GlyGen 30379171
S1411 Phosphorylation PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus
S1422 Phosphorylation PhosphoSitePlus
S1445 Phosphorylation PhosphoSitePlus
S1462 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K179 T179 Biomuta DOID:1319 / brain cancer [ cosmic ]
K227 N227 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S273 F273 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S320 I320 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S408 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S463 C463 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S471 F471 Biomuta DOID:1319 / brain cancer [ icgc ]
S492 P492 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S515 R515 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S518 P518 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S521 T521 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S523 F523 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K578 E578 Biomuta DOID:363 / uterine cancer [ cosmic ]
T658 I658 Biomuta DOID:363 / uterine cancer [ icgc ]
S697 Y697 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S736 A736 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S767 T767 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S769 L769 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S808 F808 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S889 T889 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S920 L920 Biomuta DOID:263 / kidney cancer [ cosmic ]
K1043 N1043 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1092 Y1092 Biomuta DOID:363 / uterine cancer [ icgc ]
S1203 I1203 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1207 C1207 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1210 N1210 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1341 L1341 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1363 N1363 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1377 H1377 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1445 N1445 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]