iPTMnet Report for P30281 (CCND3)
Protein Information
UniProt AC / UniProt ID | P30281 / CCND3_HUMAN |
Protein Name | G1/S-specific cyclin-D3 |
Gene Name | Name: CCND3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P30281 |
PRO Name | G1/S-specific cyclin-D3 (human) |
Definition | A G1/S-specific cyclin-D3 that is encoded in the genome of human. |
Short Label | hCCND3 |
Category | organism-gene |
P30281 (CCND3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T9 | Phosphorylation | score1 | PhosphoSitePlus | |||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
C189 | Methylation | score1 | IEDB | 31844290 | ||
T261 | Phosphorylation | score1 | PhosphoSitePlus | |||
S263 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S264 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
S282 | Phosphorylation | score1 | PhosphoSitePlus | |||
T283 | Phosphorylation | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor | 15252116, 15326477, 17709384, ... | ||
T283 | Phosphorylation | O15264 (MAPK13) | score3 | neXtProt PhosphoSitePlus | 15326477 | |
T283 | Phosphorylation | P49841 (GSK3B) | score4 | PhosphoSitePlus Signor | 16331257, 15252116 | |
T283 | Phosphorylation | P53778 (MAPK12) | score3 | neXtProt PhosphoSitePlus | 15326477 | |
T283 | Phosphorylation | Q15759 (MAPK11) | score3 | neXtProt PhosphoSitePlus | 15326477 | |
T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
T288 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T261 | S261 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S263 | C263 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T283 | N283 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T283 | I283 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
T283 | A283 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
T283 | P283 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |