Protein Information

Cytoscape View


UniProt AC / UniProt ID P30281 / CCND3_HUMAN
Protein Name G1/S-specific cyclin-D3
Gene Name Name: CCND3
Organism Homo sapiens (Human)

PRO ID PR:P30281
DAG View
PRO Name G1/S-specific cyclin-D3 (human)
Definition A G1/S-specific cyclin-D3 that is encoded in the genome of human.
Short Label hCCND3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30281 (CCND3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
C189 Methylation IEDB 31844290
T261 Phosphorylation PhosphoSitePlus
S263 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S264 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S274 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus   UniProt 19690332
T281 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
T283 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15252116, 15326477, 17709384, ...16331257, 33122824
T283 Phosphorylation O15264 (MAPK13) neXtProt   PhosphoSitePlus 15326477
T283 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 16331257, 15252116
T283 Phosphorylation P53778 (MAPK12) neXtProt   PhosphoSitePlus 15326477
T283 Phosphorylation Q15759 (MAPK11) neXtProt   PhosphoSitePlus 15326477
T285 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S263 Phosphorylation HPRD 18669648
S264 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T261 S261 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S263 C263 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T283 N283 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T283 I283 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T283 A283 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
T283 P283 Biomuta DOID:2531 / hematologic cancer [ cosmic ]