iPTMnet Report for P30154 (PPP2R1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30154 / 2AAB_HUMAN
Protein Name Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Gene Name Name: PPP2R1B
Organism Homo sapiens (Human)

PRO ID PR:P30154
DAG View
PRO Name serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (human)
Definition A serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform that is encoded in the genome of human.
Short Label hPPP2R1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30154 (PPP2R1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K46 Ubiquitination PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K200 Acetylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
R278 Methylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
C402 S-Nitrosylation dbSNO 22178444
K428 Ubiquitination PhosphoSitePlus
K454 Sumoylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
K497 Ubiquitination PhosphoSitePlus
C524 Methylation IEDB 31844290
K539 Ubiquitination PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
K573 Sumoylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD 18452278
T49 Phosphorylation HPRD 18452278
T59 Phosphorylation HPRD 18452278
S212 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD 18452278
T49 Phosphorylation HPRD 18452278
T59 Phosphorylation HPRD 18452278
K200 Ubiquitination PhosphoSitePlus
S212 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K46 N46 Biomuta DOID:4159 / skin cancer [ cosmic ]
S48 P48 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K175 T175 Biomuta DOID:1324 / lung cancer [ cosmic ]
K386 N386 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
K578 * Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]