iPTMnet Report for P30086 (PEBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30086 / PEBP1_HUMAN
Protein Name Phosphatidylethanolamine-binding protein 1
Gene Name Name: PEBP1
Synonyms:PBP,PEBP;
Organism Homo sapiens (Human)

PRO ID PR:P30086
DAG View
PRO Name phosphatidylethanolamine-binding protein 1 (human)
Definition A phosphatidylethanolamine-binding protein 1 that is encoded in the genome of human.
Short Label hPEBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30086 (PEBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus   UniProt 24275569
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
K39 Acetylation PhosphoSitePlus
T42 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 19413330, 23186163, 18669648, ...25104559, 20068231
K47 Ubiquitination PhosphoSitePlus
T51 Phosphorylation HPRD   PhosphoSitePlus 19562805, 19664995, 19651622, ...18669648, 20166139, 20068231
S52 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...17081983, 19562805, 18767875, 19664995, 19690332, 19651622, 18669648, 24275569, 20166139, 19415658, 20068231
S54 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 23186163, 24275569, ...20068231
S60 Phosphorylation PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K80 Acetylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus   UniProt 24275569
S99 Phosphorylation HPRD   PhosphoSitePlus 20166139
S104 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
Y120 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y125 Phosphorylation HPRD   PhosphoSitePlus 20068231
R129 Methylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
C133 Methylation IEDB 31844290
K150 Acetylation PhosphoSitePlus
S153 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 14654844, 12551925, 21689459, ...24286018, 28529999, 25231108, 24275569, 19103740, 20166139, 27540684, 27470585, 20068231, 19551145
S153 Phosphorylation P05129 (PRKCG) HPRD 14654844, 20166139, 12551925, ...20068231
S153 Phosphorylation P05771 (PRKCB) HPRD 14654844, 20166139, 12551925, ...20068231
S153 Phosphorylation P17252 (PRKCA) HPRD   PhosphoSitePlus 14654844, 20166139, 12551925, ...20068231
S153 Phosphorylation Q05513 (PRKCZ) HPRD 14654844, 20166139, 12551925, ...20068231
S153 Phosphorylation Q05655 (PRKCD) HPRD   PhosphoSitePlus   Signor 14654844, 20166139, 12551925, ...20068231
C168 Methylation IEDB 31844290
C168 S-Nitrosylation dbSNO 19483679
Y169 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P30086 (PEBP1) S153 Q9H492 (MAP1LC3A) unknown eFIP 27540684
Phosphorylation P30086 (PEBP1) T42 P04049 (RAF1) unknown eFIP 25104559
Phosphorylation P30086 (PEBP1) S153 P04049 (RAF1) unknown eFIP 21689459
Phosphorylation P30086 (PEBP1) S153 P04049 (RAF1) unknown eFIP 19551145


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S52 R52 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S54 L54 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
K62 R62 Biomuta DOID:3571 / liver cancer [ cosmic ]
K62 Q62 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K80 N80 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S104 F104 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S109 T109 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S109 L109 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R129 G129 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y181 H181 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]