iPTMnet Report for P30050 (RPL12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30050 / RL12_HUMAN
Protein Name Large ribosomal subunit protein uL11
Gene Name Name: RPL12
Organism Homo sapiens (Human)

PRO ID PR:P30050
DAG View
PRO Name 60S ribosomal protein L12 (human)
Definition A 60S ribosomal protein L12 that is encoded in the genome of human.
Short Label hRPL12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30050 (RPL12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
C17 S-Nitrosylation dbSNO 19483679, 2212679, 22126794, ...26338901
K31 Ubiquitination PhosphoSitePlus
S38 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18691976, 21406692, 23186163, ...16964243, 18847512, 30220558, 18669648, 20068231, 17081983
K40 Acetylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus   UniProt 36638793
K54 Acetylation PhosphoSitePlus   UniProt 19608861
K54 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
R67 Methylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus   UniProt 36638793
K99 Acetylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
R114 Methylation PhosphoSitePlus
S126 Phosphorylation IEDB   PhosphoSitePlus 27920218
T128 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
C141 S-Nitrosylation dbSNO 2212679, 22126794, 22178444, ...19366988, 18335467
C162 S-Nitrosylation dbSNO 19483679, 26338901
S165 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation HPRD 15592455, 20068231
S38 Phosphorylation HPRD 19413330, 18691976, 18212344, ...20058876, 19664994, 19664995, 19691289, 17322306, 18669648, 19651622, 19415658, 20068231, 20068230
S138 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R114 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S165 I165 Biomuta DOID:363 / uterine cancer [ icgc ]