iPTMnet Report for P30047 (GCHFR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30047 / GFRP_HUMAN
Protein Name GTP cyclohydrolase 1 feedback regulatory protein
Gene Name Name: GCHFR
Synonyms:GFRP;
Organism Homo sapiens (Human)

PRO ID PR:P30047
DAG View
PRO Name GTP cyclohydrolase 1 feedback regulatory protein (human)
Definition A GTP cyclohydrolase 1 feedback regulatory protein that is encoded in the genome of human.
Short Label hGCHFR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30047 (GCHFR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K36 Acetylation PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K36 N36 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y45 C45 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y48 S48 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]