iPTMnet Report for P29992 (GNA11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P29992 / GNA11_HUMAN
Protein Name Guanine nucleotide-binding protein subunit alpha-11
Gene Name Name: GNA11
Synonyms:GA11;
Organism Homo sapiens (Human)

PRO ID PR:P29992
DAG View
PRO Name guanine nucleotide-binding protein subunit alpha-11 (human)
Definition A guanine nucleotide-binding protein subunit alpha-11 that is encoded in the genome of human.
Short Label hGNA11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P29992 (GNA11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
R20 Methylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
C144 S-Nitrosylation dbSNO 26338901
S154 Phosphorylation PhosphoSitePlus   RLIMS-P 17646429
K158 Ubiquitination PhosphoSitePlus
T162 Phosphorylation HPRD   PhosphoSitePlus 20068231
T169 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K52 R52 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K98 E98 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K102 E102 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
C144 R144 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K282 N282 Biomuta DOID:1612 / breast cancer [ cosmic ]