iPTMnet Report for P29972 (AQP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P29972 / AQP1_HUMAN
Protein Name Aquaporin-1
Gene Name Name: AQP1
Synonyms:CHIP28;
Organism Homo sapiens (Human)

PRO ID PR:P29972
DAG View
PRO Name aquaporin-1 (human)
Definition An aquaporin-1 that is encoded in the genome of human.
Short Label hAQP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P29972 (AQP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T157 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22334691, 17522053
S236 O-Glycosylation GlyGen   PhosphoSitePlus 18984734
T239 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22334691, 17522053
Y253 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S262 Phosphorylation HPRD 18691976, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S236 G236 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y253 C253 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y253 F253 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]