iPTMnet Report for P29728 (OAS2)
Protein Information
| UniProt AC / UniProt ID | P29728 / OAS2_HUMAN |
| Protein Name | 2'-5'-oligoadenylate synthase 2 |
| Gene Name | Name: OAS2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P29728 |
| PRO Name | 2'-5'-oligoadenylate synthase 2 (human) |
| Definition | A 2'-5'-oligoadenylate synthase 2 that is encoded in the genome of human. |
| Short Label | hOAS2 |
| Category | organism-gene |
DAG ViewP29728 (OAS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score2 | UniProt | 2211721 | ||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K360 | Acetylation | score1 | PhosphoSitePlus | |||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C361 | Methylation | score1 | IEDB | 31844290 | ||
| S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K378 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C381 | Methylation | score1 | IEDB | 31844290 | ||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K399 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S417 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K433 | Acetylation | score1 | PhosphoSitePlus | |||
| K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K440 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S466 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C606 | Methylation | score1 | IEDB | 31844290 | ||
| K622 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K661 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K681 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K187 | T187 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T250 | I250 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] | |
| C361 | Y361 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C361 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S423 | F423 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S466 | R466 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S468 | C468 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| K661 | N661 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] |
