iPTMnet Report P29466 CASP1

UniProt AC / UniProt ID	P29466 / CASP1_HUMAN
Protein Name	Caspase-1 precursor
Gene Name	Name: CASP1 Synonyms:IL1BC,IL1BCE;
Organism	Homo sapiens (Human)

PRO ID	PR:P29466 DAG View
PRO Name	caspase-1 (human)
Definition	A caspase-1 that is encoded in the genome of human.
Short Label	hCASP1
Category	organism-gene

	Select/align proteoforms across species

Expanded View

Site	PTM Type	Score	Source	PMID
S16	Phosphorylation	score1	PhosphoSitePlus
T21	Phosphorylation	score1	PhosphoSitePlus
T32	Phosphorylation	score1	PhosphoSitePlus
K37	Ubiquitination	score1	PhosphoSitePlus
K44	Ubiquitination	score1	PhosphoSitePlus
T49	Phosphorylation	score1	PhosphoSitePlus
K53	Ubiquitination	score1	PhosphoSitePlus
K134	Ubiquitination	score3	PhosphoSitePlus UniProt	30065070
K148	Ubiquitination	score1	PhosphoSitePlus
S149	Phosphorylation	score1	PhosphoSitePlus
K158	Ubiquitination	score1	PhosphoSitePlus
K204	Ubiquitination	score1	PhosphoSitePlus
T226	Phosphorylation	score1	PhosphoSitePlus
S227	Phosphorylation	score1	PhosphoSitePlus
K268	Ubiquitination	score1	PhosphoSitePlus
K274	Ubiquitination	score1	PhosphoSitePlus
K278	Ubiquitination	score1	PhosphoSitePlus
S306	Phosphorylation	score1	PhosphoSitePlus
K319	Ubiquitination	score1	PhosphoSitePlus
K320	Ubiquitination	score1	PhosphoSitePlus
K325	Ubiquitination	score1	PhosphoSitePlus
S376	Phosphorylation	score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S376	Phosphorylation	Q13153 (PAK1)	score1	HPRD	15561713

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S198	Phosphorylation		score1	PhosphoSitePlus
	T203	Phosphorylation		score1	PhosphoSitePlus

Site	Variant	Source	Disease [Sample source]
T32	K32	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
K37	Q37	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K53	N53	Biomuta	DOID:363 / uterine cancer [ icgc ]
S149	L149	Biomuta	DOID:363 / uterine cancer [ icgc ]
S149	*	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S198	Y198	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S198	F198	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
T203	A203	Biomuta	DOID:2394 / ovarian cancer [ cosmic ]
K204	T204	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
K204	Q204	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S227	Y227	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S227	C227	Biomuta	DOID:1793 / pancreatic cancer [ cosmic ]
K268	N268	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
K319	R319	Biomuta	DOID:1324 / lung cancer [ icgc ]
K319	N319	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]

Or input other organisms

iPTMnet Report for P29466 (CASP1)