iPTMnet Report for P29322 (EPHA8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P29322 / EPHA8_HUMAN
Protein Name Ephrin type-A receptor 8 precursor
Gene Name Name: EPHA8
Synonyms:EEK,HEK3,KIAA1459;
Organism Homo sapiens (Human)

PRO ID PR:P29322
DAG View
PRO Name ephrin type-A receptor 8 (human)
Definition An ephrin type-A receptor 8 that is encoded in the genome of human.
Short Label hEPHA8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P29322 (EPHA8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T86 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
Y478 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PRO
Y616 Phosphorylation P29322 (EPHA8) neXtProt   phospho.ELM   PRO   Signor 10498895
T704 Phosphorylation PhosphoSitePlus
Y715 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
Y793 Phosphorylation PhosphoSitePlus
Y839 Phosphorylation P29322 (EPHA8) neXtProt   phospho.ELM   Signor 10498895
T905 Phosphorylation PhosphoSitePlus
T907 Phosphorylation PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y616 Phosphorylation P29322 (EPHA8) HPRD 10498895
Y839 Phosphorylation P29322 (EPHA8) HPRD 10498895
Site PTM Type PTM Enzyme Score Source PMID
T434 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus


P29322 (EPHA8) as PTM Enzyme



Substrate Site Score Source PMID
P29322 (EPHA8) Y616 HPRD   neXtProt   phospho.ELM   Signor 10498895
P29322-1 (EPHA8) Y839 HPRD   neXtProt   phospho.ELM   Signor 10498895


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047302 (hEPHA8/SigPep-/Phos:1) pY610,pY616 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T86 A86 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S87 N87 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S224 P224 Biomuta DOID:363 / uterine cancer [ icgc ]
S225 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T434 I434 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y610 S610 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T704 N704 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y839 S839 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y839 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T905 P905 Biomuta DOID:2531 / hematologic cancer [ cosmic ]