iPTMnet Report for P29120 (PCSK1)
Protein Information
UniProt AC / UniProt ID | P29120 / NEC1_HUMAN |
Protein Name | Neuroendocrine convertase 1 precursor |
Gene Name | Name: PCSK1 Synonyms:NEC1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P29120 |
PRO Name | neuroendocrine convertase 1 (human) |
Definition | A neuroendocrine convertase 1 that is encoded in the genome of human. |
Short Label | hPCSK1 |
Category | organism-gene |
P29120 (PCSK1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
T632 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus UniProt | 23584533, 23234360 | ||
T640 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S643 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T87 | S87 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S643 | F643 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |