iPTMnet Report for P28845 (HSD11B1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28845 / DHI1_HUMAN
Protein Name 11-beta-hydroxysteroid dehydrogenase 1
Gene Name Name: HSD11B1
Synonyms:HSD11,HSD11L,SDR26C1;
Organism Homo sapiens (Human)

PRO ID PR:P28845
DAG View
PRO Name 11-beta-hydroxysteroid dehydrogenase 1 (human)
Definition An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of human.
Short Label hHSD11B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28845 (HSD11B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
K56 Methylation PhosphoSitePlus
N123 N-Glycosylation GlyGen   UniProt 29741879, 19159218
N162 N-Glycosylation GlyGen   UniProt 29741879, 19159218
S196 Phosphorylation PhosphoSitePlus
C241 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N123 S123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S196 Y196 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]