iPTMnet Report for P28838 (LAP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28838 / AMPL_HUMAN
Protein Name Cytosol aminopeptidase
Gene Name Name: LAP3
Synonyms:LAPEP,PEPS;
Organism Homo sapiens (Human)

PRO ID PR:P28838
DAG View
PRO Name cytosol aminopeptidase (human)
Definition A cytosol aminopeptidase that is encoded in the genome of human.
Short Label hLAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28838 (LAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus   UniProt 24275569
T211 Phosphorylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus   UniProt 19608861
K221 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus   UniProt 20068231
S288 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
C445 S-Nitrosylation dbSNO 26338901
K455 Acetylation PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
C462 Methylation IEDB 31844290
K469 Ubiquitination PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
K489 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T33 Phosphorylation HPRD 20068231
Y41 Phosphorylation HPRD 20068231
S238 Phosphorylation HPRD 20068231
T285 Phosphorylation HPRD 20068231
S296 Phosphorylation HPRD 20068231
S318 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y41 H41 Biomuta DOID:1324 / lung cancer [ cosmic ]
K103 T103 Biomuta DOID:1324 / lung cancer [ cosmic ]
K221 N221 Biomuta DOID:1324 / lung cancer [ cosmic ]
K356 Q356 Biomuta DOID:1324 / lung cancer [ cosmic ]
K469 Q469 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K489 N489 Biomuta DOID:10534 / stomach cancer [ cosmic ]