iPTMnet Report for P28827 (PTPRM)
Protein Information
| UniProt AC / UniProt ID | P28827 / PTPRM_HUMAN |
| Protein Name | Receptor-type tyrosine-protein phosphatase mu precursor |
| Gene Name | Name: PTPRM Synonyms:PTPRL1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P28827 |
| PRO Name | receptor-type tyrosine-protein phosphatase mu (human) |
| Definition | A receptor-type tyrosine-protein phosphatase mu that is encoded in the genome of human. |
| Short Label | hPTPRM |
| Category | organism-gene |
DAG ViewP28827 (PTPRM) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N131 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970, 29671580, ... | ||
| N246 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
| N249 | N-Glycosylation | score1 | GlyGen | 23090970 | ||
| N406 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 17761881, 29391424, ... | ||
| N414 | N-Glycosylation | score4 | GlyGen UniProt | 17761881, 29391424 | ||
| N454 | N-Glycosylation | score3 | GlyGen UniProt | 17761881 | ||
| S524 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S525 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S533 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N534 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
| S536 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S540 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N544 | N-Glycosylation | score3 | GlyGen UniProt | 17761881 | ||
| T637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T726 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T785 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S790 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S820 | O-Glycosylation | score1 | GlyGen | 34019948, 28657654 | ||
| S820 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S821 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S823 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S824 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T826 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T847 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S853 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K862 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S917 | Phosphorylation | score1 | IEDB | 35494241 | ||
| Y929 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y935 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1182 | N-Glycosylation | score1 | GlyGen | 29391424 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N131 | N-Glycosylation | score1 | PRO | 29671580 | ||
| T264 | Phosphorylation | score0 | HPRD | 18767875 | ||
| Y273 | Phosphorylation | score0 | HPRD | 18767875 | ||
| S821 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S823 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S824 | Phosphorylation | score0 | HPRD | 18669648 | ||
| Y929 | Phosphorylation | score0 | HPRD | 18578522 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N249 | I249 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| N544 | K544 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T637 | K637 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
